Elimination of HIV Reservoirs

HIV and aids have for over two decades eluded even the most trained doctors. Doctors have over the years been researching on HIV reservoirs and eradication try.

The examination of viral reservoirs has mainly been focused on constituents of peripheral blood, but current findings show that tissue sites host the wide majority of infected cells. as a result, there remains doubt concerning the cause of persistent HIV in patients on suppressive ART. A question doctors has always wanted to answer is which cells results to the viral reservoir at the time of treatment and which cells are the source of constant viremia. To examine this they have phylogenetically equated viral genomes from the haunting viremia to viral genomes insulated from different cell types.

HIV stands for human immunodeficiency virus which causes assumed immunodeficiency syndrome better known as AIDS. Reform minded failure of the immune system causes the body to lack the ability to defend itself from opportunistic ailments. For someone to be infected by the human immunodeficiency virus the following status must have occurred. Sexual intercourse allowing bodily fluid like semen pre-ejaculate and vaginal fluids to enter the body, Transfer of blood from an infected person, and breast milk from an septic woman. HIV virus can also be transferred from an septic mother to her child at the time of birth. Blood should be thoroughly screened for HIV before transfusion to a patient.

Recently there has been treatment of HIV and AIDS with antiretroviral drugs which reduces both the early death of a dupe. Antiretroviral medication has helped to reduce the number of deaths by AIDS and new infections in many parts of the world Intensified awareness and precautionary actions, as well as the lifelike course of the epidemic, have also played a major role. Recently researchers have discovered a way of elimination of HIV Reservoirs.

In the occurrence that CD4 + T cell numbers decline below a critical level, immunity is lost, and the body becomes increasingly more prone to opportunistic disease. HIV infects vital cells in the human immune system such as CD4 + T cells, dendrites and macrophages. HIV infection leads to low levels of CD4 + T cells through three main mechanisms : direct viral destruction of infected cells, heightened levels of apoptosiss infected cells ; and the devastation of infected CD4 + T cells.

A certain scholar believed that a cure for HIV infection can be realized, but also took the complexity of the situation involved and the situation of delineating all the possible contributing factors. He noted that efforts are ongoing to appraise whether the result can be duplicated ; even though acute myelocytic leukemia is relatively rare, there are likely to be a number of cases annually in people with HIV. Doctors are tirelessly looking a way of elimination of HIV reservoirs. It seems that in the near future the dream to have a cure for HIV will be realized. The Anti Retroviral treatment was a major step towards the fulfillment of saving the world from HIV and aids. This will agnise the dream of a healthy world.

Article Reference: Elimination of HIV Reservoirs

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